- Title
- Global Cardio Oncology Registry (G-COR): Registry Design, Primary Objectives, and Future Perspectives of a Multicenter Global Initiative
- Creator
- Teske, Arco J.; Moudgil, Rohit; Sverdlov, Aaron L.; Cheng, Richard K.; Makhoul, Silvia; Ghosh, Arjun K.; Szmit, Sebastian; Zaha, Vlad; Addison, Daniel; Zhang, Lili; Herrmann, Joerg; Chong, Jun H.; López-Fernández, Teresa; Agarwala, Vivek; Iakobishvili, Zaza; Guerrero, Patricia; Yang, Eric H.; Leja, Monika; Akhter, Nausheen; Guha, Avirup; Okwuosa, Tochukwu M.; Silva, Carolina C.; Collier, Patrick; Barac, Ana; DeCara, Jeanne; Bauer, Brenton; Lenneman, Carrie E.; Sadler, Diego; Brown, Sherry Ann; Deswal, Anita; Neilan, Tomas G.; Ganatra, Sarju; Abdel Qadir, Husam; Menon, Venu
- Relation
- Circulation: Cardiovascular Quality and Outcomes Vol. 16, Issue 10, no. e009905, p. 718-728
- Publisher Link
- http://dx.doi.org/10.1161/CIRCOUTCOMES.123.009905
- Publisher
- Lippincott Williams & Wilkins
- Resource Type
- journal article
- Date
- 2023
- Description
- BACKGROUND: Global collaboration in cardio-oncology is needed to understand the prevalence of cancer therapy-related cardiovascular toxicity in different risk groups, practice settings, and geographic locations. There are limited data on the socioeconomic and racial/ethnic disparities that may impact access to care and outcomes. To address these gaps, we established the Global Cardio-Oncology Registry, a multinational, multicenter prospective registry. METHODS: We assembled cardiologists and oncologists from academic and community settings to collaborate in the first Global Cardio-Oncology Registry. Subsequently, a survey for site resources, demographics, and intention to participate was conducted. We designed an online data platform to facilitate this global initiative. RESULTS: A total of 119 sites responded to an online questionnaire on their practices and main goals of the registry: 49 US sites from 23 states and 70 international sites from 5 continents indicated a willingness to participate in the Global Cardio-Oncology Registry. Sites were more commonly led by cardiologists (85/119; 72%) and were more often university/teaching (81/119; 68%) than community based (38/119; 32%). The average number of cardio-oncology patients treated per month was 80 per site. The top 3 Global Cardio-Oncology Registry priorities in cardio-oncology care were breast cancer, hematologic malignancies, and patients treated with immune checkpoint inhibitors. Executive and scientific committees and specific committees were established. A pilot phase for breast cancer using Research Electronic Data Capture Cloud platform recently started patient enrollment. CONCLUSIONS: We present the structure for a global collaboration. Information derived from the Global Cardio-Oncology Registry will help understand the risk factors impacting cancer therapy-related cardiovascular toxicity in different geographic locations and therefore contribute to reduce access gaps in cardio-oncology care. Risk calculators will be prospectively derived and validated.
- Subject
- cardiology; cardiotoxicity; cardiovascular disease; hematology; myocarditis; SDG 3; SDG 10; Sustainable Development Goals
- Identifier
- http://hdl.handle.net/1959.13/1495510
- Identifier
- uon:54028
- Identifier
- ISSN:1941-7713
- Language
- eng
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Goal 10: Reduced Inequalities
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